As the calendar flips to November, the toll of half of an NFL season is starting to become apparent. Both the Patriots and Colts turned in lengthy injury reports on Wednesday, including key players on both sides.

The Patriots were without four players at practice on Wednesday, including three offensive starters. Wide receiver DeVante Parker (knee) highlights that group. Parker left Sunday’s win over the Jets after the first play with was later revealed to be a knee strain. Reports earlier this week indicated Parker’s status for Sunday is up in the air, with Wednesday’s practice attendance being the first indication since either way.

(Click here to subscribe to Patriots Audio on 98.5 The Sports Hub.)

In addition to Parker, running back Damien Harris (illness) and center David Andrews (concussion) missed practice on the offensive side of the ball. On defense, safety Devin McCourty (not injury related) was a non-participant.

Of the seven players listed as limited for the Patriots, three are new additions to the injury report this week. Running back Pierre Strong (hamstring), defensive end Deatrich Wise (ankle), and special teamer Matthew Slater (hamstring) all appear to have left the Jets game dealing with injuries.

The remaining limited players are defensive tackle Christian Barmore (knee), linebacker Josh Uche (hamstring), and safeties Adrian Phillips (shoulder) and Kyle Dugger (ankle). Wide receivers Nelson Agholor and Kendrick Bourne, offensive linemen Mike Onwenu and Isaiah Wynn, linebacker Anfernee Jennings, and cornerback Jonathan Jones were all removed from the report after appearing last week.

As for the Colts, they had eight players miss practice on Wednesday. That includes All-Pro running back Jonathan Taylor (ankle), and former Patriots cornerback Stephon Gilmore (rib). Center Ryan Kelly (knee), who missed last year’s matchup, was limited, and star defensive tackle DeForest Buckner (shoulder) was a full participant but still listed on the injury report.

Alex Barth is a writer and digital producer for 985TheSportsHub.com. Any opinions expressed do not necessarily reflect those of 98.5 The Sports Hub, Beasley Media Group, or any subsidiaries. Thoughts? Comments? Questions? Looking for a podcast guest? Let him know on Twitter @RealAlexBarth or via email at [email protected].