A week after allowing a season-high six sacks, the Patriots’ offensive line will once again be short-handed on Sunday. On Friday’s injury report, the team ruled out center David Andrews (concussion) and right tackle Marcus Cannon (concussion).

Andrews will miss his second game in a row after getting hit in the head late in the team’s Monday Night loss to the Chicago Bears two weeks ago. James Ferentz filled in for him at center last week.

Cannon has started the last two games at right tackle for the Patriots and played significantly in three others, often replacing Isaiah Wynn. That won’t be an option this week, after Cannon appeared on the injury report on Thursday with his concussion. Yodny Cajuste, who returned last week from a thumb injury that landed him on IR, will provide tackle depth in this game.

In addition to Andrews and Cannon, the Patriots also ruled out wide receiver DeVante Parker (knee) for the game. Parker strained his knee last week, and it was previously reported he was likely to miss this week’s matchup.

Seven Patriots are questionable for the game. That includes running back Damien Harris (illness), who was a limited participant on Friday after missing practice Wednesday and Thursday. Rookie cornerback Jack Jones (illness) was added to the report on Friday after not participating in practice.

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Running back Pierre Strong Jr. (hamstring), defensive linemen Christian Barmore (knee) and Deatrich Wise (ankle), linebacker Josh Uche (hamstring), and safety Kyle Dugger (ankle) are all questionable as well. All five were limited all week.

As for the Colts, they ruled out four players, including All-Pro running back Jonathan Taylor (ankle). Starting left tackle Dennis Kelly (calf/ankle) is questionable.

Alex Barth is a writer and digital producer for 985TheSportsHub.com. Any opinions expressed do not necessarily reflect those of 98.5 The Sports Hub, Beasley Media Group, or any subsidiaries. Thoughts? Comments? Questions? Looking for a podcast guest? Let him know on Twitter @RealAlexBarth or via email at abarth@985TheSportsHub.com.